Sami Giryes, Zaher S. Azzam, Reem Ismael-Badarneh, Norberto Krivoy and Gidon Berger Pages 7 - 9 ( 3 )
Herein, we report a 70-year-old male patient, with recurrent multiple hepatic abscesses, that was admitted to the internal medicine department for treatment of Carbapenem Resistant Escherichia Coli (CRE) bacteremia.The patient was treated with Tigecycline; few days later, he developed "Disseminated Intravascular Coagulation (DIC)" like coagulation study abnormality that seemed to be related to Tigecycline treatment. Upon discontinuing it, the DIC-like condition was resolved. Tigecycline should be considered as a possible etiological factor in patients with DIC-like, and this therapy should be withdrawn immediately in suspected cases.
Coagulation disorder, DIC, hypofibrinogenemia, Tigecycline, thrombocytopenia.
Department of Internal Medicine “B”, Rambam Health Care Campus, P.O. Box 9602, Haifa, 31096;