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An Uncommon Case of Symptomatic Multiple Meningiomas with Bilateral Compressive Optic Neuropathy Rapidly Induced under Cyprotero ne Acetate Treatment

[ Vol. 12 , Issue. 2 ]

Author(s):

Chafik Keilani and Samir Abada   Pages 134 - 139 ( 6 )

Abstract:


Introduction: Multiple meningiomas growth in patients under cyproterone acetate (CPA) is now well known. However, time between initial CPA intake and diagnosis remains unclear.

Methods: The exposure time differs in each reported case: from 2 to 10 years. We present the case of an old man with acute visual impairment caused by an unusual bilateral optic nerve compression by three likely planum sphenoidale meningiomas rapidly induced by the admistration of CPA for prostatic adenocarinoma.

Results and Conclusion: This case is the first reported with a short exposure time (7 months) to CPA treatment before diagnosis of multiple meningiomas and stabilization on clinical follow-up after CPA treatment discontinuation.

Keywords:

Papilledema, bilateral optic nerve compression, multiple meningiomas, cyproterone acetate, pharmacovigilance, exposure time.

Affiliation:

CHNO des quinze-vingts, Faculty of Medicine Pierre et Marie Curie (Paris VI), 28 Rue de Charenton, 75 571 Paris, Department of Ophthalmology, Hôpital François Quesnay, 2 boulevard Sully, 78201 Mantes-la-Jolie Cedex, Paris

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