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Comparison of the Effects of Metoprolol and Bisoprolol on Lipid and Glucose Profiles in Cardiovascular Patients

[ Vol. 14 , Issue. 1 ]


Ahmad Abdulrahman Almeman*, Yasir Ahmed Beshir and Ahmad Hamad Aldosary   Pages 27 - 30 ( 4 )


Background: Cardioselective beta-blockers may affect glucose or lipid profiles.

Objective: We sought to compare the effects of two beta-blockers, metoprolol and bisoprolol, as the most commonly used drugs in cardiology, on glucose and lipid profiles in patients with cardiovascular diseases.

Methods: We conducted a retrospective cross-sectional matched study at Prince Sultan Cardiac Center in Burydah in August 2017. Patient records were screened, and adult patients with cardiovascular disorders who were treated with a stable dose of metoprolol or bisoprolol were included. Parameters related to glucose and lipid metabolism were compared using the Student’s t-test between the two groups.

Results and Conclusion: The metoprolol and bisoprolol arms included 204 and 200 patients, respectively.


Metoprolol, bisoprolol, triglycerides, glucose, lipid, triglyceride.


Clinical Pharmacology and Therapeutics Department, Qassim University, Buraydah, Qassim, Interventional Cardiology Department, Prince Sultan Cardiac Center, Buraydah, Qassim, Family and Community Medicine Department, Unaizah College of Medicine and Medical Sciences, Qassim University, Qassim

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