Ajita Kapur and Harmeet Singh Rehan* Pages 1 - 3 ( 3 )
Among the first line anti-tubercular drugs (ATDs), ethambutol has been rarely associated to cause drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. A 34-year-old woman presented in an out-patient department of Dermatology with fever, skin eruptions, eosinophilia, hyperinflated lung fields and deranged liver enzymes after 35 days of the initiation of ATDs. The patient recovered completely after stopping ethambutol and administration of topical and systemic corticosteroids. Based on the available evidences of de-challenge and re-challenge of suspected drugs, ethambutol was certainly implicated to cause DRESS syndrome.
Drug reaction with eosinophilia and systemic symptoms syndrome, ethambutol, adverse drug reaction, drug-induced
Department of pharmacology Lady Hardinge Medical College and associated hospitals, Department of pharmacology Lady Hardinge Medical College and associated hospitals